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991.
The chronic Pseudomonas aeruginosa lung infection in cystic fibrosis (CF) is characterized by a pronounced antibody response and microcolonies surrounded by numerous polymorphonuclear neutrophils (PMN). Poor prognosis is correlated with a high antibody response to P. aeruginosa antigens. An animal model of this infection was established in two strains of mice: C3H/HeN and BALB/c, generally known as Th1 and Th2 responders, respectively, which were challenged with alginate-embedded P. aeruginosa. Mortality was significantly lower in C3H/HeN compared to BALB/c mice (p < 0.025). P. aeruginosa was cleared more efficiently in C3H/HeN mice and significantly more C3H/HeN mice showed normal lung histopathology (p < 0.02), and we found significantly fewer microabscesses in C3H/HeN mice than in BALB/c mice (p < 0.005). In supernatants from P. aeruginosa antigen and concanavalin A-stimulated spleen cells from the two strains of mice, the interferon-(IFN-) gamma levels were higher, whereas IL-4 levels were lower in C3H/HeN mice than in BALB/c mice. The implications of these findings for CF patients with chronic P. aeruginosa lung infection are discussed.  相似文献   
992.
Using an enhanced multiple output domino logic (EMODL) implementation of a carry lookahead adder (CLA), sums of several consecutive bits can be built in one nFET tree with a single carry-in. Based on this result, a new sparse carry chain architecture is proposed for the CLA adder. We demonstrate the design approach using a 32-b adder, and show that only four carries are sufficient for generating all sums, with a consequent reduction in the number of stage delays. Using a 1.2-μm CMOS technology, we verify our simulation procedures by fabrication and measurement of a 2.7 ns critical path  相似文献   
993.
StudyonHotDeformationCracksofSteelD2UsingProcesingMapGaoShan,LiuXianghua,WangGuodongABSTRACTThehotdeformationbehaviorsofsteel...  相似文献   
994.
王宝华 《材料工程》1997,(6):42-42,38
利用宽300mm、长/宽=1的横向CTT试样对国产铝钛双金属板做了常规力学性能测定,并按航标测定了KR曲线,经过柔度法和K值计算,分别测得了KRi和ai数据,确定了临界的KC值通过性能数据对比,研制的材料达到了进口料的性能要求。  相似文献   
995.
Conventional charge pump circuits use a fixed switching frequency that leads to power efficiency degradation for loading less than the rated loading. This paper proposes a level shifter design that also functions as a frequency converter to automatically vary the switching frequency of a dual charge pump circuit according to the loading. The switching frequency is designed to be 25 kHz with 12 mA loading on both inverting and noninverting outputs. The switching frequency is automatically reduced when loading is lighter to improve the power efficiency. The frequency tuning range of this circuit is designed to be from 100 Hz to 25 kHz. A start-up circuit is included to ensure proper pumping action and avoid latch-up during power-up. A slow turn-on, fast turn-off driving scheme is used in the clock buffer to reduce power dissipation. The new dual charge pump circuit was fabricated in a 3-μm p-well double-poly single-metal CMOS technology with breakdown voltage of 18 V, the die size is 4.7×4.5 mm2. For comparison, a charge pump circuit with conventional level shifter and clock buffer was also fabricated. The measured results show that the new charge pump has two advantages: (1) the power dissipation of the charge pump is improved by a factor of 32 at no load and by 2% at rated loading of 500 Ω and (2) the breakdown voltage requirement is reduced from 19.2 to 17 V  相似文献   
996.
该文研究罐装部分液体汽车在转弯制动工况下,由于液体货物质心位置的变化对行驶稳 定性的影响。文中建立了有关力学模型和数学模型,分析研究了罐体内装载不同量液体对汽车转弯制动时横摆角速度的影响规律。  相似文献   
997.
结合本钢的生产实际,对炼焦煤的最佳配比作了比较具体的分析,同时对资源,质量、成本也作了比较详细的调查,并提出了本钢焦化厂最佳配煤比方案,由此可看出,最大限度地降低采购成本,继续开发合理的配煤比例,具有广阔的前景。  相似文献   
998.
论述了BEe30-1-1冷凝管生产工艺的优点及主要问题,对现行工艺提出了改进方案。  相似文献   
999.
FATIGUE CRACK GROWTH UNDER MODE II LOADING   总被引:1,自引:0,他引:1  
Abstract— The behavior of fatigue crack growth for low and medium carbon steels, an austenitic stainless steel and an aluminum alloy under pure Mode II loading was investigated experimentally, using cruciform specimens. The results show that under pure Mode II loading, fatigue crack propagation has three possibilities, namely, bifurcation into two branches, propagation along the original Mode II direction, and the mixture of these two situations, depending on the material. The growth rate da/dN vs. ΔKII relation for Mode II propagation is similar to a Pans type law for Mode I growth. Fractographic observations by optical microscopy and SEM were made also on all specimens tested. When a crack branched, striations parallel to the crack front which were often associated with Mode I fatigue crack growth were observed and long marks parallel to the crack propagation direction were also found for slanted fracture surfaces. When a crack propagated along the original Mode II direction, many frictional marks parallel to the crack propagation direction were observed.  相似文献   
1000.
Formulas for the two-carrier third-order intermodulation distortion in semiconductor lasers have been reported by many authors. The authors refine the formula further and illustrates the difference in results arising from the refinement, for typical laser parameters.<>  相似文献   
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